Case It!
caseitproject.org
What it is
Case It! is a free framework for collaborative case-based learning in molecular biology. Its v705 software simulates laboratory procedures on DNA and protein sequences, including PCR, qPCR, gel electrophoresis, restriction enzyme digestion, ELISA, microarrays, and Southern and Western blots. It supports plasmid DNA, labelled gels, and locating restriction enzyme sites, including Cas9 sites, in double-stranded DNA. Connections to bioinformatics software and websites support sequence alignment and tree-building, and sequence search is listed as useful for undergraduate research. The download includes DNA and protein sequences cited in case descriptions on topics such as genetic and infectious diseases. Case It Mobile presents selected cases through scenarios and videos of simulated procedures on phones and tablets. Cases not converted for mobile and custom sequences require v705. The project says v705 runs on current Windows and Mac systems and documents an M-series Mac setup using UTM and Windows 11 Pro. Educational users can download it free after submitting a form.
Spec sheet
- Purpose
- Case It provides a framework for collaborative case-based learning in molecular biology.Read 2 Oct 2026 · caseitproject.org
- Bioinformatics
- Case It integrates with bioinformatics software and websites for sequence alignment and tree-building.Read 2 Oct 2026 · caseitproject.org
- CRISPR features
- The software supports plasmid DNA, 5′-labelled gels, and searching and viewing restriction enzyme sites, including Cas9 sites, in double-stranded DNA.Read 2 Oct 2026 · caseitproject.org
- Download access
- Students, instructors, and IT professionals can download the software free for educational use after submitting a form; the page says names and email addresses are kept confidential.Read 2 Oct 2026 · caseitproject.org
- Included cases
- The download includes DNA and protein sequences referenced by case descriptions, covering subjects such as genetic and infectious diseases.Read 2 Oct 2026 · caseitproject.org
- Lab procedures
- Listed procedures include qPCR, SNP and expression microarrays, restriction enzyme digestion, gel electrophoresis, PCR, ELISA, Southern and Western blots, and dot blots.Read 2 Oct 2026 · caseitproject.org
- Maker credits
- The credits page names Mark Bergland, Karen Klyczek, and Chi-Cheng Lin for software and says Case It Software is authored with Director MX.Read 2 Oct 2026 · caseitproject.org
- Mobile access
- Case It Mobile offers selected cases on smartphones and tablets through case scenarios and videos of simulated procedures, without downloading v705.Read 2 Oct 2026 · caseitproject.org
- Mobile limitation
- Cases not converted to mobile format and use of custom sequences require downloading Case It v705.Read 2 Oct 2026 · caseitproject.org
- Operating systems
- The project says v705 runs on current Windows and Mac operating systems and documents an M-series Mac setup using UTM and Windows 11 Pro.Read 2 Oct 2026 · caseitproject.org
- Sequence search
- The project lists sequence search capabilities as useful for undergraduate research applications.Read 2 Oct 2026 · caseitproject.org
- Simulation
- Case It v705 performs common laboratory procedures on DNA or protein sequences.Read 2 Oct 2026 · caseitproject.org
Plans and prices
Strong points and limits
Strong points
- Simulates a broad set of DNA and protein procedures.
- Integrates sequence alignment and tree-building tools.
- Includes sequences referenced by case descriptions.
- Offers selected cases through a mobile app.
- Free for educational use.
Limits
- Custom sequences require downloading v705.
- Some cases are not available in mobile format.
- Educational download requires submitting a form.
Who it suits
It suits instructors and learners using case-based molecular biology activities, including undergraduate research applications. Students, instructors, and IT professionals can download it for educational use.
Case It! in depth
Read the full write-up
Overview
Case It! is a molecular biology learning framework built around collaborative case work and simulated lab procedures. It is best suited to students and instructors exploring DNA- and protein-based investigations. Its educational version costs nothing, but the full range of cases and custom-sequence work requires v705 rather than the mobile app.
Key features
Case It v705 simulates a broad set of methods: PCR and qPCR, restriction enzyme digestion, gel electrophoresis, SNP and expression microarrays, ELISA, and Southern, Western, and dot blots. Connecting several procedures to case materials gives learners a way to consider how different methods relate to a biological question. The breadth is useful for molecular biology courses, but the focus is specialized rather than a general-purpose science learning suite.
CRISPR-related functions include support for plasmid DNA and 5′-labelled gels, as well as searching and viewing restriction enzyme sites—including Cas9 sites—in double-stranded DNA. Integration with bioinformatics software and websites supports sequence alignment and tree-building; sequence search is also relevant to undergraduate research applications. These features make v705 the stronger fit for sequence-based investigation, not just guided case viewing.
Downloads include the DNA and protein sequences referenced in case descriptions, with subject matter including genetic and infectious diseases. Case It Mobile offers selected cases on phones and tablets through scenarios and videos of simulated procedures. It avoids installing v705 for supported cases, but cases not converted to mobile format and custom-sequence work require the desktop software.
Pricing
Case It v705 educational use costs nothing. The free plan is for educational use, with no free trial. Students, instructors, and IT professionals can download it after submitting a form; educational access makes it a practical option for classroom use without a software charge. The Mobile app offers selected cases, while v705 is needed for custom sequences and cases that have not been converted for mobile.
Platforms
Case It supports Android, iOS, macOS, web, and Windows. Mobile access is for selected cases on smartphones and tablets. v705 runs on current Windows and Mac operating systems; an M-series Mac setup is documented using UTM and Windows 11 Pro, so that route involves a Windows virtual-machine setup rather than a native M-series workflow.
Who it's for
Choose Case It! for molecular biology teaching or learning that benefits from case materials, simulated procedures, and connections to sequence analysis. Its mix of virtual labs, biology simulations, and assessment tools serves learners at mixed levels. It is less suitable when the priority is broad anatomy content or a mobile-only experience with every case and custom sequences.
Pros and cons
Pro: The free educational v705 plan combines case-linked sequences with simulations spanning multiple common molecular biology procedures.
Pro: Bioinformatics integration and Cas9-site viewing extend the work beyond procedure demonstrations to sequence investigation.
Con: Mobile access covers selected cases only; other cases and custom sequences require downloading v705.
Con: The documented M-series Mac setup uses UTM and Windows 11 Pro, adding setup complexity for those users.
Alternatives
For a broader biology-learning directory, browse Biology Learning Software. Choose 3D Organon instead for anatomy learning with a free guest entry point and a paid student desktop plan at $74.50 a year. BioDigital Human is a better fit for 3D anatomy and physiology models, with a free personal plan capped at 10 model views per month and five saved models.
PraxiLabs may suit learners seeking a short trial of virtual simulations: its free plan provides one month and three simulations, while its monthly plan is $6.99 a month. For genetics problems through a freely accessible web or downloadable tool, consider StarGenetics or Virtual Genetics Lab II; the latter covers problems involving one to three genes. BioMan Biology is another option for interactive games, virtual labs, and learning activities, with an ad-supported free standard site. Choose Anatomyka for paid, multi-platform anatomy study, or Embase AI if its scope is the one you need and you are prepared to request a demo for custom pricing.
Verdict
Case It! is a strong choice for instructors and students who want free, case-based molecular biology work tied to simulated procedures and sequence analysis. Its main advantage is the combination of lab-method breadth, case materials, and bioinformatics connections at no educational charge. Look elsewhere if you need a complete mobile catalog, custom-sequence work on mobile, or a broader anatomy-focused learning tool.
Verdict
Case It! combines simulated lab procedures, case materials, and bioinformatics connections for molecular biology learning. Mobile access covers selected cases; v705 is required for custom sequences and other cases.
Where Specifiction places it
- Biology Learning Software#8 of 247.9