Axelium vs Rayyan
Axelium
axelium.ai
Rayyan
rayyan.aiSide by side
| Figure | Axelium | Rayyan |
|---|---|---|
| Price from | $29/mo | $4.99/mo |
| Free plan | Yes | Yes |
| Free trial | — | — |
| Open source | — | — |
| Web | Yes | Yes |
| iOS | — | Yes |
| Android | — | Yes |
| API | — | Yes |
| Plans published | 5 | 5 |
| Spec score · AI Literature Review Software | 8.3 (#8) | 8.1 (#11) |
| Audience | The site describes use for individual researchers, pharma and HEOR teams, CROs and consultancies, HTA bodies, and clinical guideline committees. | Rayyan describes its intended organization users as pharma, medical-device, CRO, university, healthcare, government, and health technology assessment teams. |
| Integrations | It lists reference imports from EndNote, Zotero, Mendeley, Embase, and Web of Science; database sources include PubMed, ClinicalTrials.gov, EuropePMC, OpenAlex, CENTRAL, MAUDE, and ERIC. | Rayyan accepts exported reference files from external databases and reference managers; it says there is no direct database connection. |
| Support | The contact page provides [email protected] for existing users and says the team replies within 1–2 business days. | The pricing page lists Standard support for Free and Essential, priority support for Advanced and Business / Academic, and dedicated support for Enterprise. |
| Workflow | Its listed 11-stage workflow includes protocol, search, screening, full-text, extraction, RoB 2.0, GRADE, statistics, network meta-analysis, reporting, and living reviews. | Its review workflow covers reference import, collaboration, deduplication, title and abstract screening, full-text screening, data extraction, risk-of-bias assessment, and reporting. |
Plans
Axelium
- FreeFree
- Researcher$29 a month
- Professional$79 a month
- Team$266 a month
- EnterprisePriced on request
Rayyan
- FreeFree
- Essential$4.99 a month
- Advanced$8.33 a month
- Business / Academic$41.67 a month
- EnterprisePriced on request
In their own words
Axelium
Axelium is an AI-assisted platform for systematic reviews and meta-analyses, spanning evidence search, screening, analysis, reporting, and living reviews. Its 11 stages include protocol, search, screening, full-text review, extraction, RoB 2.0, GRADE, statistics, network meta-analysis, reporting, and living reviews. The maker says AI extracts structured values while deterministic code calculates statistics, and data points link to snippets in original PDFs. Listed methods include pairwise and network synthesis, Cochrane RoB 2.0, GRADE certainty ratings, CERQual, and PRISMA-style reporting. It imports references from tools and databases including EndNote, Zotero, PubMed, ClinicalTrials.gov, and Web of Science; exports include DOCX, XLSX, RIS, BibTeX, and RevMan. Team controls include roles, comments, dual-person sign-off, conflict adjudication, and versioned audit snapshots. A free plan includes one lifetime review and one seat; Researcher costs $29 a month. Human validation is needed for screening suggestions, extracted values, risk-of-bias assessments, and draft reports. Recurring statistical refresh for living-review network meta-analysis is paused, though scheduled cycles can import, screen, and extract new evidence.
Rayyan
Rayyan is a platform for teams carrying out systematic evidence reviews, with workflows intended to be transparent, auditable, and reproducible. Its process spans reference import, collaboration, deduplication, title and abstract screening, full-text screening, data extraction, risk-of-bias assessment, and reporting. ResearchPilot AI Reviewer screens articles against criteria set by the user and gives decisions with reasoning notes. The Analyzer suggests inclusion or exclusion with justification, while the researcher retains final decision-making. ResearchPilot can also extract answers to custom questions from PDFs and metadata, highlight relevant passages, and let users inspect the answers. References are imported from exported files rather than a direct database connection. The API offers programmatic access to reviews, references, decisions, and metadata, plus workflow automation and external integrations. Rayyan is available on Android, iOS, web, and through an API. The Free plan allows three active reviews and two free reviewers; paid options start at $8.33 a month per seat, billed annually. Free mobile access is limited; Essential and higher provide unlimited mobile access.