Axelium vs Systematicly

Axelium is an AI-assisted platform for systematic reviews and meta-analyses, spanning evidence search, screening, analysis, reporting, and living reviews. Its 11 stages include protocol, search, screening, full-text review, extraction, RoB 2.0, GRADE, statistics, network meta-analysis, reporting, and living reviews. The maker says AI extracts structured values while deterministic code calculates statistics, and data points link to snippets in original PDFs. Listed methods include pairwise and network synthesis, Cochrane RoB 2.0, GRADE certainty ratings, CERQual, and PRISMA-style reporting. It imports references from tools and databases including EndNote, Zotero, PubMed, ClinicalTrials.gov, and Web of Science; exports include DOCX, XLSX, RIS, BibTeX, and RevMan. Team controls include roles, comments, dual-person sign-off, conflict adjudication, and versioned audit snapshots. A free plan includes one lifetime review and one seat; Researcher costs $29 a month. Human validation is needed for screening suggestions, extracted values, risk-of-bias assessments, and draft reports. Recurring statistical refresh for living-review network meta-analysis is paused, though scheduled cycles can import, screen, and extract new evidence.

Systematicly is a web-based research platform for systematic reviews, primary research, ethics applications and research proposals. It can analyze a topic using PICO, PECO or SPIDER frameworks and produce Boolean searches for databases including PubMed, Scopus, Web of Science, ERIC and PsycINFO. Reviewers can screen titles and abstracts and upload PDFs for structured field extraction. Analysis options include 1,033 statistical functions, plain-English analysis, meta-analysis, plots, sensitivity analysis and GRADE assessment. The platform lists eight review types, plus publishing tools such as AI-assisted manuscripts and proposals, PRISMA diagrams, journal recommendations and reviewer response letters. It retrieves PDFs automatically from PMC, Unpaywall and EuropePMC, and supports ClinicalTrials.gov imports and several reference formats. The free Explorer plan is limited to three active personal drafts, one lifetime feasibility preview and three lifetime Evidence Answers. Paid one-time options include a single Evidence Answer for $19, paid once and literature review packages from $149, paid once. The security page says user data is not used to train AI models; Anthropic’s commercial API may retain inputs and outputs for up to 30 days for trust and safety monitoring.