Benchling Notebook vs Indigo ELN

Benchling Notebook is a cloud-based electronic lab notebook for capturing, accessing, and sharing scientific work. It keeps experiments, metadata, collaboration, and analysis together, with search, templates, and schemas for organizing records. Teams can share and co-edit entries using tags, comments, task assignments, and role-based permissions. Entries can link results to samples and experimental data, while the product describes LIMS integration for connecting samples and results. Benchling says the notebook supports 21 CFR Part 11 requirements through audit-ready electronic records and signatures. Listed ecosystem integrations include AWS, Google Cloud Platform, Jupyter, Snowflake, and Titian Mosaic, with instrument connections through Benchling Automation. Developer tools include REST APIs, a Python SDK, webhooks, an application framework, and a Postgres SQL data warehouse. Benchling states that data is encrypted at rest with AES 256-bit encryption and in transit with TLS 1.2 or higher, and that it maintains SOC 2 Type 2 attestation and ISO 27001:2022 certification. The free academic plan includes Notebook and Molecular Biology; industry pricing is customized.

Indigo ELN is a free electronic lab notebook for creating, storing, retrieving, and sharing chemistry records. It organizes work into projects, notebooks, experiments, and components, while allowing experiment templates and added components without changing the core code. Ketcher provides chemical structure editing, and Indigo handles reaction rendering and chemical property calculations. Searches can use entity attributes, or product structures and reaction schemes with BingoDB integration. APIs connect customer services, databases, and electronic signature services. Role-based authorities and access control lists govern projects, notebooks, and experiments. Pages can be printed to PDF, and SDF files can be imported or exported. The system runs on the web and can be self-hosted; the maker says a Docker image is available, with documented local Docker and AWS deployment. The core product is free under GNU GPL version 3 and provided without warranty. EPAM offers paid customization, integration, support, and maintenance. The demo environment is unavailable while work continues toward a public version 3.0 environment.