Labfolder vs Signals Notebook

Labfolder is a browser-based electronic lab notebook for documenting, organizing, and managing experiments. Researchers can work with different data types, track changes, and export research data. Teams can share projects with custom access settings, message each other, assign tasks, and use electronic signatures. Labregister links inventory records to Labfolder notes and is included at no extra cost. Labfolder offers an HTTP-based REST API for working with data in third-party applications, and lists Dropbox, Figshare, and Labregister among its in-ELN apps. The company says data is processed and stored in Germany, protected with 256-bit SSL encryption, and backed up daily. The browser product needs no installation, and on-premise deployment is available. The site says it works in modern browsers on Windows, Mac, and Linux, including desktop, tablet, and smartphone devices. It has no mobile app and does not support offline editing. Labfolder describes support for GLP and FDA 21 CFR Part 11 through record history, electronic signatures, secure storage, and role-based access control. A free plan and 14-day trial are listed, but pricing depends on user count and requires a quote.

Signals Notebook is a cloud-based electronic laboratory notebook for capturing, organizing, and sharing research data. It is presented for pharmaceutical, biotechnology, chemical, materials, and food, flavor, and fragrance teams. Experiment records support flexible templates, rich text, embedded media, folders, tags, full-text search, automatic versioning, and audit trails. Native ChemDraw integration handles stoichiometry and searches by CAS number, structure, or name, with PubChem safety information. Teams can share notebooks, comment, review and approve entries with electronic signatures, receive notifications, and apply granular permissions. Named connections include Spotfire, Signals DLX instrument capture, inventory management, and open APIs for LIMS, ERP, and other systems. The product describes 21 CFR Part 11 support, SOC 2 and ISO 27001 security programs, encryption, multifactor authentication, and automated backups. It runs in browsers on web, macOS, Windows, and API environments.