OpenEvidence vs Perplexity

OpenEvidence is a medical information platform for clinical questions, available on the web, iOS and Android. Its answers include inline citations, while EvidenceGrade shows the strength of cited evidence beneath an AI answer. The app listing describes access to more than 35 million peer-reviewed papers, over 300 medical journals, and FDA and CDC sources. Named partners or collaborators include NEJM, JAMA and its specialty journals, NCCN, Nature and Cochrane; NCCN material includes treatment algorithms. Clinicians can earn CME and MOC credits by asking questions. Additional listed tools include ambient documentation, secure patient calls through Dialer and hands-free Voice Mode. OpenEvidence’s Trust Center lists SOC 2 Type 2 and HIPAA certifications. Access requires healthcare-professional status verification, and the free plan is for verified U.S. healthcare professionals. The product page says medical professionals use it at more than 10,000 U.S. care centers. Support is available at [email protected].

Perplexity is an answer engine that searches the open web and returns answers with inline citations. It can search files and connected apps alongside the web, and can select among more than 20 leading models, including ChatGPT, Gemini, Claude, and Nemotron. Deep Research conducts searches across many sources and produces a report. Access is available on Android, iOS, macOS, web, and Windows, with an API also listed. The free plan has limited weekly use for simple questions. Pro costs $20 a month and adds Computer, premium data sources, web search, files, apps, model council, and model selection. Max costs $200 a month and offers higher limits for Deep Research, resource generation, file uploads, and monthly video creation. Enterprise Pro is $40 a month per seat; Enterprise Max is $325 a month per seat. Enterprise plans bill by seat, and API use requires separate credits. Perplexity lists more than 400 app connectors.