POMSnet Aquila MES vs Signals Notebook

POMSnet Aquila MES is a web-based manufacturing execution system for GMP-regulated pharmaceutical and life sciences production. It is designed for pharmaceutical, biotech, and cell and gene therapy processes. Core functions include recipe and specification management, materials and equipment management, production orders, recipe execution, electronic batch records, and device history. Specification Management includes more than 100 S88 phases for recipe construction, while the system provides more than 50 standard cGMP reports for production, quality, audits, and regulatory review. Quality Management supports 21 CFR Part 11 electronic signatures and records, FIFO or FEFO policies, expiry and retesting workflows, and lot disposition controls. Aquila supports two-way batch traceability and lot tracking. Customers can deploy it on premises or through SaaS cloud delivery. Its HTML5 interface is mobile-ready and touch-enabled. Integration tools cover ERP, LIMS, CAPA, training, document management, asset management, devices, and process control systems. Pricing is available on request.

Signals Notebook is a cloud-based electronic laboratory notebook for capturing, organizing, and sharing research data. It is presented for pharmaceutical, biotechnology, chemical, materials, and food, flavor, and fragrance teams. Experiment records support flexible templates, rich text, embedded media, folders, tags, full-text search, automatic versioning, and audit trails. Native ChemDraw integration handles stoichiometry and searches by CAS number, structure, or name, with PubChem safety information. Teams can share notebooks, comment, review and approve entries with electronic signatures, receive notifications, and apply granular permissions. Named connections include Spotfire, Signals DLX instrument capture, inventory management, and open APIs for LIMS, ERP, and other systems. The product describes 21 CFR Part 11 support, SOC 2 and ISO 27001 security programs, encryption, multifactor authentication, and automated backups. It runs in browsers on web, macOS, Windows, and API environments.