StarGenetics vs Virtual Genetics Lab II

StarGenetics is a free simulator for Mendelian genetics crosses, intended to teach genetics concepts and experimental design. Its stated audience ranges from high school biology to advanced undergraduate biology. Students can use visualizers for cows, fish, flies, peas, a smiley face and yeast. Instructor resources cover genetic crosses, Punnett squares, complementation, epistasis, gene linkage and mapping, and tetrad analysis. Instructors can customize exercises using Excel workbooks in XLS format. The Punnett Square tool summarizes expected genotypic distributions for monohybrid and dihybrid crosses. Fly mating results can be viewed individually, sorted by sex and phenotype, or summarized by phenotype; DNA markers for genetic mapping are available in the Fly and Fish visualizers. Experiments can be saved to a file and reopened later. Excel export is limited to Fly exercises. StarGenetics is accessible through the web and downloadable for Linux, Windows and macOS. MIT recommends Java Web Start and provides operating-system downloads for users with limited internet connectivity. Users can submit bug reports, feature requests, comments or questions through the in-app suggestions form.

Virtual Genetics Lab II (VGLII) is a free simulation for students exploring how traits are inherited. Students cross hypothetical creatures and examine offspring, using problems that cover one to three genes. Traits can be autosomal or sex-linked, with simple dominance, co-dominance, or incomplete dominance; instructors can restrict which models are available. Model Builder lets students enter and save genetic models, and instructors can compare responses with correct answers for grading. Version 3 includes chi-squared calculations in the Summary Chart, epistasis and complementation models, and Super Crosses of up to 2,000 offspring. Desktop downloads are listed for Windows, Mac OS X, and Linux/UNIX, and the download page says VGLII requires Java 7 or higher. The maker also describes jsVGL, a browser-based version that does not use Java and can load and save work. The maker says VGLII will no longer be supported, while support will continue for jsVGL. Some macOS versions may show an error about loading the Java Runtime Environment; a workaround uses the app's VGLII.jar file.