OpenClinica vs Signals Notebook
OpenClinica
openclinica.comSignals Notebook
revvitysignals.comSide by side
| Figure | OpenClinica | Signals Notebook |
|---|---|---|
| Price from | $750/mo | — |
| Free plan | — | — |
| Free trial | Yes | Yes |
| Open source | Yes | — |
| Web | Yes | Yes |
| Windows | Yes | Yes |
| macOS | Yes | Yes |
| Linux | Yes | — |
| iOS | Yes | — |
| Android | Yes | — |
| API | Yes | Yes |
| Self-hosted | Yes | — |
| Plans published | 4 | 1 |
| Spec score · Life Sciences Software | 8.8 (#1) | 8.1 (#5) |
| Headquarters | Needham, Massachusetts, USA | Waltham, Massachusetts, USA |
| Integrations | The product advertises standards-based EHR connectivity, Apple Health collection and links to common clinical-research systems such as CTMS, labs, payments and IxRS through integrations or APIs. | The product page names ChemDraw, Spotfire, Signals DLX instrument data capture, inventory management, and open APIs for LIMS, ERP, and other systems. |
| Intended users | The company says it focuses on small to midsize sponsors, CROs, and academic research teams. | The product is presented for research teams in pharmaceuticals and biotechnology, chemicals and materials, and food, flavor, and fragrance. |
| Product | OpenClinica is an eClinical platform combining electronic data capture, eConsent, eCOA, randomization, EHR-to-EDC, analytics, and patient recruitment. | Signals Notebook is a cloud-native electronic laboratory notebook for capturing, organizing, and sharing research data. |
| Support | Commercial support is advertised as available 24 hours a day, five days a week on weekdays, with ticketing and telephone access. | The trial FAQ points users to in-product help resources including a Quick Start Guide, training videos, and a User Guide. |
Plans
OpenClinica
- Launch$750 a month
- Core$3,000 a month
- Advanced$3,750 a month
- Enterprise & AcademicPriced on request
In their own words
OpenClinica
OpenClinica has no write-up on Specifiction yet; its figures are above.
Signals Notebook
Signals Notebook is a cloud-based electronic laboratory notebook for capturing, organizing, and sharing research data. It is presented for pharmaceutical, biotechnology, chemical, materials, and food, flavor, and fragrance teams. Experiment records support flexible templates, rich text, embedded media, folders, tags, full-text search, automatic versioning, and audit trails. Native ChemDraw integration handles stoichiometry and searches by CAS number, structure, or name, with PubChem safety information. Teams can share notebooks, comment, review and approve entries with electronic signatures, receive notifications, and apply granular permissions. Named connections include Spotfire, Signals DLX instrument capture, inventory management, and open APIs for LIMS, ERP, and other systems. The product describes 21 CFR Part 11 support, SOC 2 and ISO 27001 security programs, encryption, multifactor authentication, and automated backups. It runs in browsers on web, macOS, Windows, and API environments.