Phoenix ELN vs RSpace

Phoenix ELN is a free, open-source electronic lab notebook for Windows, designed for organic, organometallic and peptide chemistry. Experiment protocols can place reactants, reagents, solvents, comments, products, images and files in workflow order. Adding materials supplies stoichiometric information such as equivalents and millimoles. The self-learning materials database contains nearly 200 commonly used reagents, solvents and auxiliaries, with cross-checked molecular weights and densities. An integrated drawing editor supports organic, organometallic, peptide and resin-bound structures. Reaction substructure searches work across local experiments; an optional server extends searches to finalized experiments across an organization. Phoenix ELN runs without a server connection and supports offline access. The optional in-house server adds continuous backup, experiment sharing and organization-wide searches, with an installation script for MySQL or MariaDB. Protocols export to PDF compliant with PDF/A-3b, embedding inserted documents as PDF attachments; ZIP, JPEG, PNG and TIF are also listed. Support is directed to GitHub Issues and Discussions.

RSpace is an open-source electronic research notebook and research data management platform for research workflows. Its web application supports real-time collaboration, granular sharing controls, comments and annotations, with full-text and metadata search. Chemistry teams can draw compounds and calculate stoichiometry for reaction planning, while RSpace Inventory tracks samples alongside notebook documentation. Forms provide structured fields and ontology integration for FAIR metadata. Records can be exported as HTML, XML, PDF, DOC, JSON and RO-Crate. A RESTful API supports custom integrations. RSpace states that data is encrypted at rest and over networks and supports 21 CFR Part 11 and GLP. Research Space identifies ISO 27001 and SOC 2 certification. Deployment can be self-installed, managed in a private AWS instance, or run on premises for Enterprise. Plans include a free open-source option, Team plans at $6,000 a year and $12,000 a year, and Enterprise at $34,000 a year.