OpenClinica vs RSpace
OpenClinica
openclinica.comRSpace
researchspace.comSide by side
| Figure | OpenClinica | RSpace |
|---|---|---|
| Price from | $750/mo | $500/mo |
| Free plan | — | Yes |
| Free trial | Yes | Yes |
| Open source | Yes | Yes |
| Web | Yes | Yes |
| Windows | Yes | Yes |
| macOS | Yes | Yes |
| Linux | Yes | Yes |
| iOS | Yes | — |
| Android | Yes | — |
| API | Yes | Yes |
| Self-hosted | Yes | Yes |
| Plans published | 4 | 6 |
| Spec score · Life Sciences Software | 8.8 (#1) | 8.8 (#2) |
| API | The service exposes REST web services for data exchange and bulk imports, event scheduling and participant creation. | RSpace exposes REST APIs for programmatic search, retrieval, document creation, file upload, sharing and data export. |
| Company history | The company says it has spent 20 years building eClinical software and that its EDC began for academic institutions. | Research Space says its originating company was spun out of the University of Edinburgh in 2003 by neuro-informatics researchers. |
| Compliance | The company states its platform is ICH GCP E6 (R2), 21 CFR Part 11, HIPAA, and GDPR compliant, and SOC 2 Type II and ISO 27001 certified. | Official feature material states GDPR, 21 CFR Part 11 and GLP compliance, plus suitability for NIH Data Sharing Policy requirements. |
| Deployment | OpenClinica documentation says its Enterprise offering is available as a cloud-hosted solution or a self-hosted and managed system. | Enterprise customers can choose on-premises deployment or a private AWS instance in a location of their choice. |
| Integrations | The product advertises standards-based EHR connectivity, Apple Health collection and links to common clinical-research systems such as CTMS, labs, payments and IxRS through integrations or APIs. | The site advertises more than 20 integrations spanning storage, repositories, data-management-plan tools, chemistry, biology, instruments and collaboration software. |
| Intended users | The company says it focuses on small to midsize sponsors, CROs, and academic research teams. | The company describes its work as serving researchers, research data managers, librarians, stewards, research computing specialists, and policymakers. |
| Open-source licence | The Community Edition is free, open source and distributed under the GNU LGPL licence. | The RSpace codebase is released under the GNU Affero General Public License version 3.0 or later. |
| Product | OpenClinica is an eClinical platform combining electronic data capture, eConsent, eCOA, randomization, EHR-to-EDC, analytics, and patient recruitment. | RSpace is an open-source electronic research notebook and research data management platform for research workflows. |
| Rating on G2 | 4.2 out of 5 from 24 reviews | 0.0 out of 5 from 0 reviews. |
| Self-hosting | Community Edition can be downloaded and hosted on an organization’s own Linux or Windows server, with the user responsible for implementation, validation and support. | Self-hosted deployment is supported through a WAR package and Docker Compose configuration. |
| Support | Commercial support is advertised as available 24 hours a day, five days a week on weekdays, with ticketing and telephone access. | The contact page offers a support team and knowledge base, while Enterprise includes live chat and premium email support. |
| System requirements | Documented single-server minimums are Linux Red Hat or CentOS, quad-core 2GHz CPU, 4GB RAM and 100GB disk; recommended memory is 16GB and disk 500GB. | The Docker guidance suggests at least 4 GB RAM for a dedicated machine, 8 GB for better experience, and server guidance from 8 GB RAM for under 50 users to 32 GB for 250–5000 users. |
| What it does | OpenClinica is an electronic data capture and clinical data-management platform for building and running clinical studies. | RSpace is a collaborative electronic laboratory notebook and broader research data-management platform for documenting, organizing, sharing and connecting research data. |
Plans
OpenClinica
- Launch$750 a month
- Core$3,000 a month
- Advanced$3,750 a month
- Enterprise & AcademicPriced on request
RSpace
- RSpace Open SourceFree
- Team (Academia)$6,000 a year
- Team (Commercial)$12,000 a year
- Enterprise (Academia)$34,000 a year
- Enterprise (Commercial)$34,000 a year
- InfrastructurePriced on request
In their own words
OpenClinica
OpenClinica has no write-up on Specifiction yet; its figures are above.
RSpace
RSpace is an open-source electronic research notebook and research data management platform for research workflows. Its web application supports real-time collaboration, granular sharing controls, comments and annotations, with full-text and metadata search. Chemistry teams can draw compounds and calculate stoichiometry for reaction planning, while RSpace Inventory tracks samples alongside notebook documentation. Forms provide structured fields and ontology integration for FAIR metadata. Records can be exported as HTML, XML, PDF, DOC, JSON and RO-Crate. A RESTful API supports custom integrations. RSpace states that data is encrypted at rest and over networks and supports 21 CFR Part 11 and GLP. Research Space identifies ISO 27001 and SOC 2 certification. Deployment can be self-installed, managed in a private AWS instance, or run on premises for Enterprise. Plans include a free open-source option, Team plans at $6,000 a year and $12,000 a year, and Enterprise at $34,000 a year.