Alternatives to DeSmuME

MindSpark is aimed at researchers and engineers who want to map ideas, work with citations, or shape prompts.

SkyEmu suits players who want to emulate these four handheld systems across desktop, mobile, or web platforms.

melonDS

melonDS suits people looking for Nintendo DS emulation on Windows, macOS, or Linux who can configure the required console files.

GB Enhanced+ suits users seeking an open-source emulator for Game Boy-family systems and Pokémon Mini, especially those interested in peripheral emulation.

It suits Android users looking for a free, open-source Nintendo DS emulator with save states, cheats, and multiple screen layouts.

dasShiny is aimed at users familiar with cartridge folders and recent BSNES versions who want to experiment with Nintendo DS emulation.

DS Anywhere suits users who want browser-based DS emulation with local ROM handling.

DSperate suits Linux users on AArch64 or ARMhf, particularly those using ARM handhelds.

DSVita suits PlayStation Vita users who want Nintendo DS emulation and configurable touch controls.

It suits people who want to run melonDS through a desktop or mobile web browser and use browser-based controls and saves.

NO$GBA suits Windows users who need Game Boy Advance, Nintendo DS, or DSi emulation, and developers using its debugging tools.

It suits Android users seeking an open-source Nintendo DS emulator, especially those comfortable with older software or source builds.

nds4droid suits Android smartphone users seeking a free, ad-free way to emulate Nintendo DS software.

It suits Android users who want Nintendo DS or DSi emulation with configurable graphics, layouts, and RetroAchievements.