Best Medical Billing Software in 2026
Updated
In short: Mirth Connect is ranked #1 of 28 as of 8 October 2026, ahead of PracticeSuite Medical Billing and TotalMD. The best-ranked option with a free plan is Office Ally Practice Mate. The lowest first paid tier on this page is TotalMD at $35/mo.
Medical billing software supports the work of processing claims and patient payments. Compare claim scrubbing and coding support with eligibility verification, denial management, and ERA auto-posting to assess the billing tasks each option covers. Patient payments and payment posting add further points to consider, while free-plan availability and paid-from pricing help frame cost. PracticeSuite Medical Billing, TotalMD, and Office Ally Practice Mate are among the entries. Consider which steps your team needs to handle and compare the listed capabilities with your practice’s existing billing processes.
28 medical billing software ranked on what their makers publish — plans and prices, free tiers, platforms and the facts on their own pages.
Compare all 25 in a table
| # | Tool | Score | Free plan | From | Free plan | Paid from | Eligibility verification | Denial management |
|---|---|---|---|---|---|---|---|---|
| 1 | Mirth Connect | 7.5 | Free plan | Free | — | — | Yes | Yes |
| 2 | PracticeSuite Medical Billing | 7.2 | No | — | No | — | Yes | Yes |
| 3 | TotalMD | 7.2 | No | $35/mo | No | 69 /user/mo | Yes | Yes |
| 4 | Nextech | 7.0 | No | — | — | — | — | — |
| 5 | Office Ally Practice Mate | 7.0 | Free plan | Free | Yes | — | Yes | — |
| 6 | Tebra | 7.0 | No | $199/mo | No | — | — | — |
| 7 | EZClaim | 6.8 | No | $189/mo | No | — | Yes | Yes |
| 8 | Oracle Health Revenue Cycle | 6.8 | No | — | — | — | Yes | Yes |
| 9 | CareCloud RCM | 6.6 | No | — | — | — | Yes | Yes |
| 10 | RXNT Medical Billing | 6.6 | No | — | No | — | Yes | Yes |
| 11 | AdvancedMD Medical Billing | 6.5 | No | $2,291,070/mo | No | — | Yes | Yes |
| 12 | eClinicalWorks Revenue Cycle Management | 6.5 | No | — | No | — | Yes | Yes |
| 13 | Experian Health Revenue Cycle Management | 6.5 | No | — | — | — | Yes | Yes |
| 14 | ModMed Revenue Cycle Management | 6.5 | No | — | — | — | Yes | Yes |
| 15 | Waystar | 6.5 | No | — | — | — | Yes | Yes |
| 16 | XiFin Empower RCM | 6.5 | No | — | — | — | Yes | Yes |
| 17 | Infinx Healthcare Revenue OS | 6.3 | No | $5,000/mo | No | — | Yes | Yes |
| 18 | athenaCollector | 6.2 | No | — | No | — | Yes | Yes |
| 19 | CollaborateMD | 6.1 | No | — | No | — | Yes | Yes |
| 20 | CareRight Billing and Claiming | 5.8 | No | — | — | — | — | Yes |
| 21 | Kipu RCM | 5.8 | No | — | — | — | Yes | — |
| 22 | theBillingBridge | 5.8 | No | — | Yes | — | — | Yes |
| 23 | Candid Health | 5.7 | No | — | — | — | Yes | Yes |
| 24 | Parathon | 5.7 | No | — | — | — | Yes | Yes |
| 25 | R1 Phare | 5.6 | No | — | — | — | Yes | Yes |
Is your tool on this list?
Numbered spots on this list can be sponsored, and a sponsored row is labelled as paid.
Questions about this list
Which medical billing software is ranked first on Specifiction?
Mirth Connect is ranked #1 of 28 with a score of 7.5. PracticeSuite Medical Billing is second and TotalMD third.
How many of these have a free plan?
2 of the 25 on this page publish a free plan on their own pricing pages.
Which is the cheapest paid option?
On this page, TotalMD has the lowest first paid tier we found: $35/mo.
How is this list ranked?
Ranked on what each maker publishes, the fullest spec sheet first: how deeply the product is documented, the platforms it runs on, a free tier or trial to test it, and its standing.








